panick attack testosterone

Can Testosterone Replacement Therapy Cause Panic Attacks?

It is said that testosterone replacement therapy can lead to panic attacks. Is there any scientific evidence behind this? Check out this article.

Quick summary

  • Testosterone levels can influence anxiety levels, with low levels of testosterone linked to increased anxiety.
  • Testosterone replacement therapy (TRT) has the potential to induce panic attacks due to its effect on cortisol levels.
  • To avoid the adverse effects of TRT, natural testosterone boosters such as Testogen, Testofuel, and Testolan are recommended as a safer alternative for maintaining normal testosterone levels.

The amount of anxiety you experience may also be influenced by your sexual hormones. Social anxiety can be exacerbated by fluctuations in the concentrations of the sex hormones estrogen and testosterone.

Some studies have connected low testosterone levels to greater anxiety. In fact, low levels of female hormones such as estrogen have also been associated with anxiety symptoms.

If that is true, then let’s find whether testosterone replacement therapy (TRT) plays any role in causing panic attacks or not.

Panic attacks caused to testosterone replacement therapy. Myth or fact?

Yes. It has the potential to influence hormones such as cortisol, which can trigger severe stress and panic episodes.

Although there may be a deficiency in B vitamins, in the same way that having too little testosterone can cause social anxiety, having too much testosterone can help to lessen it.

Indeed, men have a reported rate of mental illnesses that is half that of women; it may be attributed in part to the involvement of testosterone in the regulation of anxiety levels in both sexes.

Gamma-aminobutyric acid (GABA) & serotonin are two neurotransmitters that are influenced by testosterone. These two substances in the brain have been linked to panic attacks.

How to raise testosterone without replacement therapy?

TRT is the clinical standard for treating hypogonadism; however, exogenous testosterone substitutes are linked to higher stress hormone levels.

To prevent this, you can opt for natural and herb-based testosterone boosters, which supplement your body with all necessary nutrients that are needed for a healthy androgen secretion.

Some top-rated natural pills include Testogen, Testofuel, and Testolan, which you can purchase online.

Many sports personnel and athletes nowadays prefer testosterone supplements for their performance enhancement.

The current user base includes everyone from middle-aged males to elderly people to youthful athletes and everything in between.

Since more men are being identified with testosterone problems, the demand for advanced and efficient testosterone enhancement supplements continues to grow.

These supplements can help to maintain normal testosterone levels without any side effects like steroids.


In a nutshell, testosterone replacement therapy is proven to induce panic attacks because of its ability to increase the cortisol hormone.

Since in TRT, you use synthetic steroids to substitute the t-hormone, the effects will be instantaneous, and there will be a surge of cortisol hormone.

This surge can, in turn, mess up the GABA activity in your brain, eventually leading to panic attacks.

Therefore, you must rely on natural foods and nutraceutical-based testosterone boosters to increase your t-levels.

Written by Tom Knight
Fact Checked by Experts
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